N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-GLUTAMIC-ACID-GAMMA-TERT-BUTYL ESTER - Names and Identifiers
N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-GLUTAMIC-ACID-GAMMA-TERT-BUTYL ESTER - Physico-chemical Properties
Molecular Formula | C18H25NO6
|
Molar Mass | 351.39 |
Density | 1.184 |
Boling Point | 501.0±50.0 °C(Predicted) |
pKa | 3.81±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-GLUTAMIC-ACID-GAMMA-TERT-BUTYL ESTER - Introduction
Z-N-Me-Glu(OtBu)-OH (Z-N-Me-Glu(OtBu)-OH) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to pale yellow solid.
-Solubility: It can be dissolved in organic solvents, such as methanol, ethanol and dichloromethane, but it is difficult to dissolve in water.
-Melting point: approximately 60-70°C.
Use:
- Z-N-Me-Glu(OtBu)-OH is commonly used as a protecting group for amino acid derivatives in organic synthesis.
-It can be used in peptide synthesis, peptide synthesis and other organic synthesis reactions.
Preparation Method:
-Z-N-Me-Glu(OtBu)-OH can generally be synthesized by the following steps: First, N-methyl-N-benzyloxycarbonyl-L-glutamic acid and tert-butanol are reacted under basic conditions to form an ester. The tert-butanol is then deprotected using acidic conditions to generate the Z-N-Me-Glu(OtBu)-OH.
Safety Information:
-The safety level of Z-N-Me-Glu(OtBu)-OH is generally considered to be low or non-toxic.
-When using, pay attention to avoid direct contact with skin and eyes, and wear protective gloves and goggles if necessary.
-Keep away from fire and heat sources during operation to prevent fire or explosion.
-Store in a cool, dry place, away from oxidizers and combustibles.
Please note that chemical experiments and the use of chemicals should follow laboratory safety regulations, and in the case of limited or uncertain laboratory experience, the guidance of a professional chemist should be consulted.
Last Update:2024-04-09 21:01:54